Subinhibitory concentrations of licochalcone A decrease alpha-toxin production in both methicillin-sensitive and methicillin-resistantStaphylococcus aureusisolates
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چکیده
منابع مشابه
Effects of subinhibitory concentrations of antibiotics on alpha-toxin (hla) gene expression of methicillin-sensitive and methicillin-resistant Staphylococcus aureus isolates.
Concentrations of antibiotics below the MIC are able to modulate the expression of virulence-associated genes. In this study, the influence of subinhibitory doses of 31 antibiotics on the expression of the gene encoding the staphylococcal alpha-toxin (hla), a major virulence factor of Staphylococcus aureus, was investigated with a novel gene fusion protocol. The most striking observation was a ...
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Introduction: Biofilm formation in Staphylococcus aureus is a major virulence factor. Both methicillin-sensitive Staphylococcus aureus (MSSA) and methicillin-resistant Staphylococcus aureus (MRSA) are common causes of community- and hospital-acquired infections and are associated with biofilm formation. The status of biofilm-forming genes has not been explored in Jordanian nasal carriers of S. ...
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background staphylococcus aureus is associated with different infections ranging from skin and soft tissue infections to endocarditis and fatal pneumonia. s. aureus is still the most common bacterial species isolated from inpatient specimens and the second most common from outpatient specimens. today, methicillin resistant s. aureus (mrsa) isolates are present in the hospitals of most countries...
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ژورنال
عنوان ژورنال: Letters in Applied Microbiology
سال: 2010
ISSN: 0266-8254,1472-765X
DOI: 10.1111/j.1472-765x.2009.02783.x